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      Damage and disease in the human brain, including CT and PET scanning

      Lesson details

      Learning outcome

      I can describe some of the difficulties in studying and treating damage in the nervous system and brain.

      Key learning points

      1. The importance and difficulties of investigating brain function and damage, including safety and ethical considerations.
      2. Use of CT and PET scanning to study the brain.
      3. Difficulties in treating disease and damage in the nervous system and brain (e.g. lack of mitosis in neurones).
      4. Potential treatments for disease and damage in the nervous system and brain (e.g. stem cells).

      Keywords

      • Ethical - relates to whether an action and its consequences are right or wrong

      • Informed consent - consent obtained from a patient where they fully understand the procedure and its implications

      • Mitosis - a type of cell division that produces genetically identical cells

      • Stem cell - a cell that can differentiate into specialised cells

      Common misconception

      Understanding the ethics of research practices is complex and often misunderstood. The details of various brain scanning techniques are complex and also confusing.

      Ethical practices are discussed with examples and changes through history to give context. Brain scanning techniques are illustrated and explained, with follow up tasks.

      Teacher tip

      When discussing ethics and informed consent, consider this from a student's perspective: would it be right to use their social media post for my benefit without their informed consent? Be careful this doesn't go off track though!

      Content guidance

      Depiction or discussion of sensitive content

      Supervision

      Adult supervision recommended

      Licence

      This content is © Oak National Academy Limited (2026), licensed on Open Government Licence version 3.0
      except where otherwise stated. See Oak's terms & conditions
      (Collection 2).

      Lesson video

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      Prior knowledge starter quiz

      6 Questions

      Q1.
      What type of issues relate to whether an action and its consequences are right or wrong?

      Correct Answer: ethical

      Q2.
      What types of cells primarily make up brain tissue?

      fat
      Correct answer: nerve
      grey
      glandular
      muscle

      Q3.
      What is the process of ordinary cell division called?

      Correct Answer: Mitosis

      Q4.
      What are stem cells?

      cells found in the stem of any plant
      cells found in the stem of a flowering plant
      Correct answer: cells that can differentiate into other types of cell
      cells found in the stem of the brain

      Q5.
      fMRI imaging uses radiation to visualise brain activity.

      Correct Answer: electromagnetic

      Q6.
      Match the disease to its symptoms.

      Correct Answer:Parkinson's disease,parts of the brain become damaged, affects muscles, e.g. slow movement

      parts of the brain become damaged, affects muscles, e.g. slow movement

      Correct Answer:Dementia,associated with an ongoing decline of brain functioning, e.g. memory

      associated with an ongoing decline of brain functioning, e.g. memory

      Correct Answer:Epilepsy,causes frequent seizures

      causes frequent seizures

      Correct Answer:Depression,involves having a low mood that affects day-to-day living

      involves having a low mood that affects day-to-day living

      Correct Answer:Stroke,when the blood supply to part of the brain is cut off

      when the blood supply to part of the brain is cut off

      6 Questions

      Q1.
      Match the type of scan to its description.

      Correct Answer:Computerised Tomography,uses x-rays to scan a patient’s body showing slices of the body

      uses x-rays to scan a patient’s body showing slices of the body

      Correct Answer:Positron Emission Tomography,uses a radioactive substance to emit gamma rays that can be detected

      uses a radioactive substance to emit gamma rays that can be detected

      Q2.
      When embarking on research into the human brain, what should we consider?

      effectiveness of the treatment
      Correct answer: safety
      Correct answer: ethical issues

      Q3.
      Which of these statements is not an ethical issue involved in studying patients with brain damage caused by Parkinson's?

      The patient may not be able to consent to the research.
      The patient may not benefit from the research.
      Correct answer: Patient brain function may be severely limited.
      The patient may be harmed from the research.

      Q4.
      True or false? Stem cells can cure brain disease.

      true
      Correct answer: false

      Q5.
      Which of the following are true about how a PET (Positron Emission Tomography) scanner works?

      Correct answer: When the radioactive glucose decays, it emits a positron (a positive electron).
      The PET scanner detects glucose used in respiration.
      Correct answer: The PET scanner detects gamma rays released from decaying glucose molecules.
      The PET scanner detects electrons released from decaying glucose molecules.
      Correct answer: The more active a part of the brain is, the more radioactive glucose it absorbs.

      Q6.
      Neurones are very complex cells and cannot undergo to create new copies of themselves.

      Correct Answer: mitosis

      To help you plan your 10 biology lesson on: Damage and disease in the human brain, including CT and PET scanning, download all teaching resources for free and adapt to suit your pupils' needs...