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      Hormonal control of the menstrual cycle

      Lesson details

      Learning outcome

      I can explain the roles of FSH, LH, oestrogen and progesterone in controlling the menstrual cycle in human females.

      Key learning points

      1. FSH causes follicle maturation and secretion of oestrogen by the ovaries.
      2. Oestrogen causes thickening of uterus wall, secretion of LH by the pituitary gland and inhibits the release of FSH.
      3. LH causes ovulation; FSH and LH cause the mature follicle to break down and secrete progesterone.
      4. Progesterone prepares uterus lining for implantation of fertilised egg; stops secretion of LH & FSH by pituitary gland.
      5. Fall in progesterone causes menstruation.

      Keywords

      • FSH - follicle stimulating hormone, causes the follicle containing an egg to mature

      • LH - luteinising hormone causes ovulation

      • Oestrogen - a hormone that causes thickening of the uterus lining and the release of LH from the pituitary gland

      • Progesterone - maintains the uterus lining and stops the release of FSH and LH from the pituitary gland

      • Ovulation - the release of an egg from a mature follicle in the ovaries

      Common misconception

      That the menstrual cycle is not linked with reproduction; that hormones only control mood.

      Diagrams to show the clear effect of hormones on changes in the menstrual cycle and discuss the importance of the process to fertilisation.

      Teacher tip

      The final task can be presented in different ways; comic strip, poster etc.

      Equipment

      None required.

      Licence

      This content is © Oak National Academy Limited (2026), licensed on Open Government Licence version 3.0
      except where otherwise stated. See Oak's terms & conditions
      (Collection 2).

      Lesson video

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      Prior knowledge starter quiz

      6 Questions

      Q1.
      What is menstruation?

      The building up of the uterus lining.
      Correct answer: Breaking down of the uterus lining and it leaving the body.
      The monthly cycle of female hormones.
      The releasing of an egg from the ovary.
      Hormones screted by the pituitary gland.

      Q2.
      What is the name given to an egg being released from an ovary?

      Correct Answer: Ovulation

      Q3.
      Which of the following about hormones are true?

      They control our movement.
      Correct answer: They are produced by glands.
      Correct answer: They travel around the body in blood.
      The more you have, the more moody they make us.
      Correct answer: They are a chemical.

      Q4.
      Match the part to its name.

      An image in a quiz
      Correct Answer:A,fallopian tube

      fallopian tube

      Correct Answer:B,ovary

      ovary

      Correct Answer:C,cervix

      cervix

      Correct Answer:D,vagina

      vagina

      Correct Answer:E,uterus

      uterus

      Q5.
      What does fertilisation produce?

      ovules
      Correct answer: zygote
      egg
      ova
      foetus

      Q6.
      Put these in order of development.

      1 - egg cell
      2 - zygote
      3 - embryo
      4 - foetus
      5 - baby

      6 Questions

      Q1.
      What are the effects of FSH?

      It causes menstruation.
      Correct answer: It causes the ovaries to secrete oestrogen.
      Correct answer: It causes the follicle containing an egg to mature.
      It causes progesterone to be released.
      It causes the uterus lining to thicken.

      Q2.
      Put these steps of the menstrual cycle in the correct order.

      1 - uterus lining breaks down and menstruation takes place
      2 - uterus lining reforms and thickens
      3 - ovulation
      4 - uterus lining continues to thicken as egg travels down the fallopian tube
      5 - uterus lining is maintained ready for a fertilised egg

      Q3.
      Which hormone causes ovulation to take place?

      Correct Answer: LH, luteinising hormone

      Q4.
      Which hormones cause the mature follicle to break down and secrete progesterone?

      LH and oestrogen
      FSH and oestrogen
      Oestrogen and progesterone
      Correct answer: LH and FSH
      Progesterone and FSH

      Q5.
      A fall in which hormone triggers menstruation?

      Correct Answer: Progesterone

      Q6.
      Order the steps.

      An image in a quiz
      1 - FSH is released from the pituitary gland and travels to the ovaries.
      2 - A follicle matures and oestrogen is released.
      3 - Oestrogen causes uterus lining to thicken, LH to be released and inhibits FSH.
      4 - LH causes ovulation.
      5 - FSH and LH cause the mature follicle to break down and secrete progesterone.
      6 - Progesterone maintains uterus lining and prevents the secretion of FSH and LH.
      Q6 Dee-sign/Shutterstock.com

      To help you plan your 11 biology lesson on: Hormonal control of the menstrual cycle, download all teaching resources for free and adapt to suit your pupils' needs...