Choose exam board for KS4 Computer Science (GCSE)
Choose exam board for KS4 English
Choose exam board for KS4 French
Choose exam board for KS4 Geography
Choose exam board for KS4 German
Choose exam board for KS4 History
Choose tier for KS4 Maths
Choose exam board for KS4 Music
Choose exam board for KS4 Physical education (GCSE)
Choose exam board for KS4 Religious education (GCSE)
Choose exam board for KS4 Spanish

      Electron microscopy, and the size and scale of cells

      Lesson details

      Learning outcome

      You can describe the size and scale of cells and cell structures, and explain how electron microscopy has increased our understanding of sub-cellular structures.

      Key learning points

      1. Most cells are too small to be seen without a microscope.
      2. Comparison of the sizes of cells and cell structures.
      3. Light microscopes have limited magnification and resolution.
      4. Electron microscopes have greater magnification and resolution, allowing much smaller structures to be seen clearly.
      5. Electron microscopy has increased our understanding of sub-cellular structures.

      Keywords

      • Light microscope - a type of microscope that uses visible light and a system of lenses to generate magnified images of small objects

      • Magnification - making small objects appear larger in order to see more detail

      • Resolution - the minimum distance at which two distinct points of a specimen can still be seen

      • Electron microscope - a type of microscope that uses a beam of electrons instead of light. Electron microscopes have a higher magnification and resolving power than light microscopes

      Common misconception

      Pupils may think that all cells are approximately the same size.

      Calculations in the deck will allow pupils to compare the relative sizes of cells. It might be helpful to draw extra attention to this point.

      Teacher tip

      It might be helpful to print out a large version of the unit conversion table to put up in the classroom so that pupils become more familiar with the unit prefixes.

      Equipment

      calculators

      Licence

      This content is © Oak National Academy Limited (2026), licensed on Open Government Licence version 3.0
      except where otherwise stated. See Oak's terms & conditions
      (Collection 2).

      Lesson video

      Loading...

      Prior knowledge starter quiz

      6 Questions

      Q1.
      What is the term for the most basic units of living organisms?

      tissue
      Correct answer: cell
      organ
      organism

      Q2.
      In which type of cell is genetic material typically not enclosed within a membrane-bound nucleus?

      animal cell
      plant cell
      fungal cell
      Correct answer: bacterial cell

      Q3.
      Which of the following is present in both prokaryotic and eukaryotic cells?

      chloroplasts
      Correct answer: cytoplasm
      nucleus
      mitochondria

      Q4.
      What is the main purpose of a microscope?

      Correct answer: to magnify objects
      to heat samples
      to measure temperature
      to observe

      Q5.
      Which of the following are eukaryotes?

      Correct answer: plants
      bacteria
      Correct answer: animals
      Correct answer: protists
      viruses

      Q6.
      What is an electron?

      Correct answer: Part of an atom that carries a negative charge and orbits the nucleus.
      Part of an atom that carries a positive charge and is found in the nucleus.
      Part of an atom that carries no overall charge and is found in the nucleus.
      Part of an atom where most of the mass of the atom is found.

      6 Questions

      Q1.
      Which type of microscope uses electrons to view specimens in 3D?

      light microscope
      compound microscope
      Correct answer: scanning electron microscope
      transmission electron microscope

      Q2.
      In microscopy, what does the term 'resolution' refer to?

      the brightness of the light source
      making small objects appear larger in order to see more detail
      Correct answer: the distance at which two distinct points of a specimen can still be seen
      the size of the microscope stage

      Q3.
      Which microscope would be most suitable for observing detailed structures within a cell, such as chloroplasts?

      light microscope
      compound microscope
      scanning electron microscope
      Correct answer: transmission electron microscope

      Q4.
      A typical human hair has a diameter of approximately 60 micrometres (µm). What is its diameter in nanometres?

      60 nm
      600 nm
      6000 nm
      Correct answer: 60 000 nm

      Q5.
      The nucleus of a cell measures 5 micrometres (µm) in diameter. In an image, the nucleus appears as 20 millimetres. What is the magnification of the nucleus in the image?

      40x
      400x
      Correct answer: 4000x
      40 000x

      Q6.
      A plant cell has a length of 20 µm, while a bacterium measures 2 µm in length. How many times longer is the plant cell compared to the bacterium?

      5 times
      Correct answer: 10 times
      15 times
      20 times

      To help you plan your 11 biology lesson on: Electron microscopy, and the size and scale of cells, download all teaching resources for free and adapt to suit your pupils' needs...