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      Genetic engineering, including the main steps

      Lesson details

      Learning outcome

      I can describe what genetic engineering is, some potential benefits, risks and ethical issues and the main steps in the process.

      Key learning points

      1. Genetic engineering involves modifying the genome of an organism by adding DNA from another organism.
      2. The aim of genetic engineering is to introduce a desirable characteristic.
      3. Examples of genetically engineering crop plants and bacteria to benefit humans.
      4. Benefits must be weighed against risks and ethical issues.
      5. The main steps in the process of genetic engineering.

      Keywords

      • Gene - a section of DNA carrying the genetic code that provides the instructions for a feature or process

      • Genetic engineering - the process of introducing a gene from one organism into the genome of another organism

      • Risk - the chance that an outcome (usually a negative one) will occur

      • Ethical question - a question about whether something is right or wrong

      • Vector - a plasmid or virus used to introduce a gene from one organism into the genome of another organism

      Common misconception

      Over-estimating the risks of genetic engineering and genetically modified (GM) organisms.

      The lesson explores the need to weigh up possible benefits, risks and ethical questions when making decisions about genetic engineering.

      Teacher tip

      When exploring the examples, ask pupils to practice suggesting for themselves the possible benefits and risks (and to whom), and identifying ethical questions. Use prompt questions or a simple writing frame to guide their thinking.

      Content guidance

      Depiction or discussion of sensitive content

      Supervision

      Adult supervision recommended

      Licence

      This content is © Oak National Academy Limited (2026), licensed on Open Government Licence version 3.0
      except where otherwise stated. See Oak's terms & conditions
      (Collection 2).

      Lesson video

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      Prior knowledge starter quiz

      6 Questions

      Q1.
      What is the name of the molecule that contains the genetic code in all organisms ?

      lipids
      proteins
      RNA
      Correct answer: DNA

      Q2.
      __________ are long, thread-like structures made of DNA and proteins, found in the nucleus of cells.

      Cells
      Correct answer: Chromosomes
      Genes
      Nuclei

      Q3.
      __________ is a section of DNA carrying the genetic code that provides the instructions for a feature or process.

      An amino acid
      Correct answer: A gene
      A nucleotide
      A protein

      Q4.
      What are the building blocks (monomers) for DNA?

      Correct answer: nucleotides
      amino acids
      proteins
      lipids

      Q5.
      Proteins are long chains of ...

      Correct answer: amino acids.
      carbohydrates.
      lipids.
      nucleotides.

      Q6.
      Where is the DNA found in prokaryotic cells?

      in the nucleus
      in the cell wall
      in the vacuole
      Correct answer: in the cytoplasm

      6 Questions

      Q1.
      What is the main goal of genetic engineering?

      to eliminate undesirable characteristics
      to increase genetic diversity
      Correct answer: to introduce desirable characteristics
      to randomly change DNA

      Q2.
      What is a potential risk of genetically modified crops?

      native species outcompeting GM organisms
      crops with an increased nutritional value being grown
      Correct answer: GM genes being transferred to other organisms in the wild
      crops that are resistant to pests being grown

      Q3.
      What is one ethical consideration in genetic engineering?

      the complexity of the process
      the cost of genetic engineering
      the speed of genetic modifications
      Correct answer: whether it is right to modify the genetic material of living organisms

      Q4.
      What is one benefit of producing bacteria that can produce insulin?

      an increased pest resistance in crops
      an increased crop yield
      Correct answer: an improved diabetes treatment
      improved food security

      Q5.
      Put the main steps involved in genetic engineering in the correct order.

      1 - using a restriction enzyme to isolate a desirable gene
      2 - using a ligase enzyme to insert the desirable gene into a vector
      3 - using a vector to insert the desirable gene into the target cells
      4 - selecting cells that have taken up the desirable gene
      5 - growing genetically modified organisms from selected cells

      Q6.
      Which enzyme is used to join vector DNA and desirable gene DNA together at the 'sticky ends'?

      Correct answer: a ligase enzyme
      a restriction enzyme
      a polymerase enzyme
      a reverse transcriptase enzyme

      To help you plan your 11 biology lesson on: Genetic engineering, including the main steps, download all teaching resources for free and adapt to suit your pupils' needs...