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      The importance of maintaining constant conditions in the body

      Lesson details

      Learning outcome

      I can explain why it is important for humans to maintain constant conditions inside the body.

      Key learning points

      1. If conditions in the body change too much this can be dangerous to our health.
      2. Changes in body temperature affect the rate of chemical reactions and can impact enzyme activity.
      3. Changes in body temperature can lead to hypo- or hyperthermia and death.
      4. Changes in water balance in the body can lead to dehydration and death.
      5. Use of antagonistic effects to maintain a constant environment.

      Keywords

      • Enzyme - a protein that acts as a biological catalyst

      • Internal body temperature - the optimal internal temperature of our body, which is about 37°C

      • Homeostasis - the regulation of the internal conditions to maintain optimum conditions for enzyme action and all cell functions

      • Antagonistic - effectors and effects that work against each other

      Common misconception

      It is common for pupils to misunderstand the links between increased or decreased body temperature and the impact on enzyme function.

      Explanations of the effect of temperature on enzyme activity, the link between body temperature and enzyme function, and conditions such as hyper- and hypo-thermia are made and explored in this lesson.

      Teacher tip

      Use a Bunsen burner and beaker of water to explore the process of body temperature homeostasis practically. It's quick to set up but can be a real challenge to complete, and should encourage pupils to really think about how they are responding to the observed changing conditions in the beaker.

      Equipment

      Optional: Bunsen burner, tripod, gauze, heat proof mat, thermometer, beaker, ice cubes.

      Licence

      This content is © Oak National Academy Limited (2026), licensed on Open Government Licence version 3.0
      except where otherwise stated. See Oak's terms & conditions
      (Collection 2).

      Lesson video

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      Prior knowledge starter quiz

      6 Questions

      Q1.
      Below is a simplified diagram of an enzyme. What is shown by A?

      An image in a quiz
      Correct Answer: Active site, An active site, the active site

      Q2.
      Which of the following are effectors?

      Correct answer: glands
      the brain
      Correct answer: muscles
      the spinal cord
      motor neurone

      Q3.
      True or false? Enzymes are catalysts.

      Correct answer: true
      false

      Q4.
      The graph shows the rate of an enzyme controlled reaction. Point A represents the temperature for the enzyme.

      An image in a quiz
      Correct Answer: optimum, optimal

      Q5.
      The graph shows the rate of an enzyme controlled reaction. Why is the rate of reaction decreasing at point c?

      An image in a quiz
      The enzyme is being killed.
      The enzyme is too hot.
      The enzyme has run out of active sites.
      Correct answer: The enzyme is becoming denatured.
      The enzyme has run out of substrate.

      Q6.
      If a significant increase in body temperature is sustained, it can lead to ...

      hypothermia
      Correct answer: hyperthermia

      6 Questions

      Q1.
      The maintenance of a constant internal environment is known as .

      Correct Answer: homeostasis

      Q2.
      True or false? All enzymes work optimally at pH 7 and 37 °C.

      true
      Correct answer: false

      Q3.
      What name is given to enzymes whose active site has changed shape and no longer fits to its substrate?

      Correct Answer: denatured

      Q4.
      Order the statements below to describe how the body responds to an increase in body temperature.

      1 - A temperature receptor detects an increase in temperature.
      2 - A signal is sent to the coordination centre e.g. brain.
      3 - The coordination centre sends a message to the sweat glands.
      4 - Sweat glands increase sweat production.
      5 - Sweat evaporates.
      6 - The body cools down.

      Q5.
      The Oak pupils are discussing the control of water levels in the body. Who is correct?

      Jacob: You need to stay hydrated so that you can urinate.
      Correct answer: Laura: We need water for chemical reactions to take place.
      Correct answer: Sam: If you become severely dehydrated you can die.
      Lucas: The kidneys control the amount of water lost through urination.

      Q6.
      Which of the following are antagonistic effects?

      Correct answer: insulin which decreases blood sugar, and glucagon which increases blood sugar
      thyroid stimulating hormone which increases the production of thyroxine
      Correct answer: sweating to cool the body down, and shivering to warm the body up
      the brain sending signals down a relay neurone to a motor neurone

      To help you plan your 11 combined science lesson on: The importance of maintaining constant conditions in the body, download all teaching resources for free and adapt to suit your pupils' needs...