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      Errors in cell division and cancer: beyond the basics

      Lesson details

      Learning outcome

      You can describe cancer including benign and malignant tumours and explain how mutations can cause cancer.

      Key learning points

      1. Cancer is caused by uncontrolled cell growth and division which can lead to the formation of tumours.
      2. Benign tumours are usually contained within one area and do not invade surrounding tissues.
      3. Malignant tumours are cancerous, they invade surrounding tissues and can cause secondary tumours.
      4. Scientists have identified lifestyle and genetic factors that can increase the risk of developing cancer.
      5. Mutations can cause changes in DNA; this alters the nucleotide sequence and genetic code

      Keywords

      • Mutation - A change in the nucleotide sequence of DNA that can cause mutated genes.

      • Genes - Short sections of DNA that code for a specific characteristic or protein.

      • Tumour - A mass of cells that has been produced through uncontrolled cell division.

      • Benign - A tumour that is non-cancerous and contained to one area.

      • Malignant - A tumour that is cancerous and can spread.

      Common misconception

      All tumours are cancerous and dangerous.

      Students are given very clear examples of the difference between benign and malignant tumours. The difference between the two is covered in the slide deck, check for understanding questions and practice tasks.

      Teacher tip

      To help make the link between sequence of nucleotides and genes you could model some mutations within the lesson to physically see how the gene changes.

      Content guidance

      Depiction or discussion of sensitive content

      Depiction or discussion of sensitive content

      Depiction or discussion of mental health issues

      Depiction or discussion of sexual content

      Supervision

      Adult supervision required

      Licence

      This content is © Oak National Academy Limited (2026), licensed on Open Government Licence version 3.0
      except where otherwise stated. See Oak's terms & conditions
      (Collection 2).

      Lesson video

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      Prior knowledge starter quiz

      6 Questions

      Q1.
      What is a gene?

      A biological catalyst.
      Correct answer: A short section of DNA.
      A sub-cellular structure which surrounds the cell.

      Q2.
      What process is used to create new cells for growth and repair in multicellular organisms?

      meiosis
      Correct answer: mitosis
      fertilisation

      Q3.
      What does obese mean?

      Correct answer: very overweight
      very underweight
      healthy weight

      Q4.
      Which of the following is not a lifestyle factor?

      drinking alcohol
      smoking
      Correct answer: genetic disease
      using sunbeds

      Q5.
      If smoking is a risk factor for developing lung cancer, which statement is true.

      Everyone who smokes will develop lung cancer.
      People who smoke have the same risk as non-smokers for developing lung cancer.
      Correct answer: People who smoke increase their chance of developing lung cancer.

      Q6.
      is a chemical substance that carries the genetic information.

      Correct Answer: DNA, dna, D N A, d n a

      6 Questions

      Q1.
      What are tumours and cancer caused by?

      Correct answer: uncontrolled cell division
      cell division suddenly stopping
      Correct answer: changes to the DNA of cells
      the nucleus of cells dividing

      Q2.
      Which statements are usually true for benign tumours?

      Correct answer: slow growing
      invade surrounding tissue
      cancer causing
      Correct answer: contained within a membrane

      Q3.
      Which type of tumour is shown below?

      An image in a quiz
      Correct answer: malignant tumour
      benign tumour

      Q4.
      Match the lifestyle risk factor to the type of cancer it is linked to.

      Correct Answer:UV radiation,skin cancer

      skin cancer

      Correct Answer:viral infection,cervical and liver cancers

      cervical and liver cancers

      Correct Answer:smoking,lung, mouth, bowel, stomach and cervical cancers

      lung, mouth, bowel, stomach and cervical cancers

      Correct Answer:obesity,bowel, liver and kidney cancers

      bowel, liver and kidney cancers

      Q5.
      Put these statements in order to show how a tumour can form.

      1 - A mutation causes a change in the nucleotide sequence of DNA.
      2 - A gene that controls the cell cycle is changed.
      3 - Cells begin to divide uncontrollably.
      4 - A tumour is formed.

      Q6.
      What are the three types of mutation?

      insertion, addition and deletion
      insertion, deletion and replacement
      Correct answer: insertion, deletion and substitution
      conversion, deletion and substitution

      To help you plan your 10 combined science lesson on: Errors in cell division and cancer: beyond the basics, download all teaching resources for free and adapt to suit your pupils' needs...