New
New
The structure of DNA: including nucleotides
I can describe the structure of DNA and how DNA is copied during mitosis.
Lesson 3 of 6
New
New
- Year 10
- AQA
The structure of DNA: including nucleotides
I can describe the structure of DNA and how DNA is copied during mitosis.
Lesson details
Key learning points
- DNA is made of two strands, each a long polymer of nucleotides, wound together in a double helix shape.
- DNA is a polymer of four different nucleotides (A, C, G and T).
- Nucleotides in each strand of DNA pair up in a complementary way; A pairs with T, and C pairs with G.
- The DNA in chromosomes is unwound & copied during interphase, then the copies separate and the cell divides by mitosis.
- Complementary base pairing allows an exact copy of each ‘unzipped’ DNA strand to be made from free nucleotides.
Keywords
DNA - A polymer with a double helix structure that carries the genetic information.
Mitosis - A type of cell division that produces genetically identical cells.
Nucleotides - Individual subunits that make up DNA.
Polymer - A long chain of repeating subunits.
Complementary base pairing - Bases form pairs with one other base: A pairs with T, and C pairs with G.
Common misconception
Students may think that each strand of DNA is the same without recognising one strand is inverted.
The slides specifically mention the second strand is inverted and this is also reinforced using diagrams of inverted nucleotides wherever possible.
Emphasise that the nucleotides are inverted on one of the DNA strands and that each nucleotide is a monomer/subunit which is why DNA is a polymer. Can model the structure of DNA using paper with the 4 different bases cut out and then matched together.
Teacher tip
Licence
This content is © Oak National Academy Limited (2026), licensed on Open Government Licence version 3.0 except where otherwise stated. See Oak's terms & conditions (Collection 2).
Prior knowledge starter quiz
6 Questions
Q1.This image shows a model of ...
This image shows a model of ...

a bacterial cell.
a mitochondrion.
an enzyme.
Q2.Which of the following is the definition of a polymer?
Which of the following is the definition of a polymer?
A single subunit that makes up a long repeating chain.
A type of cell division that produces genetically identical cells.
Individual subunits that make up DNA.
Q3.Match each structure to its correct definition.
Match each structure to its correct definition.
Q4.What happens during interphase in the cell cycle?
What happens during interphase in the cell cycle?
The cell membrane and cytoplasm divide.
The chromatids are pulled to either end of the cell.
Q5.Which type of cell division creates two genetically identical cells?
Which type of cell division creates two genetically identical cells?
meiosis
Q6.Which term describes a cell with a membrane bound nucleus?
Which term describes a cell with a membrane bound nucleus?
Assessment exit quiz
6 Questions
Q1.Which words describe the structure of DNA?
Which words describe the structure of DNA?
monomer
single strand
Q2.DNA is made from single repeating subunits called ...
DNA is made from single repeating subunits called ...
bases.
nuclei.
phosphates.
Q3.Which of these statements about DNA are true?
Which of these statements about DNA are true?
The base A always pairs with G.
The sugar phosphate backbone includes the base of a nucleotide.
Q4.What is complementary base pairing?
What is complementary base pairing?
DNA is made from repeating bases.
DNA has a double helix structure.
DNA unwinds during interphase.
Q5.Which of the following statements about copying DNA are true?
Which of the following statements about copying DNA are true?
DNA is copied during mitosis.
Four copies of the same double helix DNA are created.
Q6.Use the diagram to match the letter to the correct part of the nucleotide.
Use the diagram to match the letter to the correct part of the nucleotide.
