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Responses of the human immune system to specific pathogens

Lesson details

Learning outcome

I can describe parts of the human immune system and how they respond to specific pathogens.

Key learning points

  1. All cells, including our body cells and pathogens, have molecules called antigens on their surface.
  2. White blood cells only respond to non-self antigens on pathogens.
  3. Lymphocytes are an important part of the human immune system and respond to antigens on specific pathogens.
  4. Lymphocytes produce antibodies against specific pathogens.
  5. Lymphocytes produce antitoxins to neutralise toxins produced by bacteria.

Keywords

  • Antigen - A molecule on the surface of a pathogen or other cell.

  • White blood cell - A type of cell in the blood that is part of the immune system and responds to pathogens.

  • Lymphocyte - A type of white blood cell that is part of the immune system and responds to specific pathogens.

  • Antibodies - Proteins produced by white blood cells against specific pathogens.

  • Antitoxins - Produced by white blood cells to neutralise toxins.

Common misconception

Mixing up scientific terms such as antigen and antibody.

The lesson explores the relationship and differences between antigens, antibodies and antitoxins.

Teacher tip

Ask the students to say the words starting with anti- out loud when you are teaching so they can learn the difference.

Equipment

None required.

Licence

This content is © Oak National Academy Limited (2026), licensed on Open Government Licence version 3.0
except where otherwise stated. See Oak's terms & conditions
(Collection 2).

Lesson video

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Prior knowledge starter quiz

6 Questions

Q1.
A microorganism that causes disease is called a ...

Correct answer: pathogen.
phagocyte.
platelet.

Q2.
The human body has defences against pathogens. The skin is an example of a defence.

Correct Answer: physical

Q3.
Tears are a chemical defence against pathogens. They contain __________ that break down pathogens.

Correct answer: enzymes
mucus
platelets
red blood cells

Q4.
Which of these are part of the immune system?

pathogens
red blood cells
Correct answer: white blood cells

Q5.
Match each part of the blood to its function.

Correct Answer:plasma,To transport waste products and hormones.

To transport waste products and hormones.

Correct Answer:platelets,To stick together to heal wounds.

To stick together to heal wounds.

Correct Answer:phagocytes,To engulf and digest pathogens.

To engulf and digest pathogens.

Correct Answer:red blood cells,To transport oxygen.

To transport oxygen.

Q6.
is the process of a white blood cell engulfing and digesting a pathogen.

Correct Answer: phagocytosis

6 Questions

Q1.
All cells, including our body cells and pathogens, have molecules on their surface called ...

antibodies.
Correct answer: antigens.
antitoxins.

Q2.
True or false? Antitoxins neutralise toxins.

Correct answer: true
false

Q3.
White blood cells called lymphocytes release proteins called that cause pathogens to clump together.

Correct Answer: antibodies

Q4.
Antibodies cause pathogens to clump together so they can be engulfed and digested by a ...

lymphocyte.
Correct answer: phagocyte.
platelet.
red blood cell.

Q5.
True or false? Lymphocytes are part of the non-specific response to pathogens.

true
Correct answer: false

Q6.
Who is correct?

Andeep: All pathogens have the same antigens on their surface.
Izzy: One lymphocyte can make antibodies against many different pathogens.
Correct answer: Sam: Each lymphocyte makes antibodies specific to an antigen on one pathogen.
Laura: Pathogens make antibodies that are recognised by a specific lymphocyte.

To help you plan your 11 biology lesson on: Responses of the human immune system to specific pathogens, download all teaching resources for free and adapt to suit your pupils' needs...