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      Using hormones to treat infertility

      Lesson details

      Learning outcome

      I can describe the use of hormones to treat some types of infertility in humans.

      Key learning points

      1. Infertility is the inability to become pregnant (conceive).
      2. In adult human females, some types of infertility are caused by problems with hormones that control the menstrual cycle.
      3. Hormones can be used as a treatment for these types of infertility.
      4. The use of hormones in IVF treatment.

      Keywords

      • Infertility - The inability to become pregnant (conceive).

      • Menstrual cycle - A monthly cycle which involves the maturation and release of an egg, and menstruation.

      • IVF - In vitro fertilisation, in which an embryo is formed in a laboratory and then inserted into the uterus of the mother.

      • FSH - Follicle stimulating hormone, which matures follicles containing eggs in the ovaries.

      • Embryo - A development stage when a fertilised egg starts to divide.

      Common misconception

      IVF is highly effective without side effects. People can already choose the features of a baby. All people can have IVF from the NHS.

      IVF is less than 40% effective and this decreases with the age of the mother over 35. Genetic testing of embryos can be used to look for a disease, but genes cannot be altered. There is criteria for receiving IVF from the NHS and it is limited.

      Teacher tip

      Pupils may wish to do the final task as a role play conversation; or the class could do further research and then debate it.

      Equipment

      None requuired.

      Content guidance

      Depiction or discussion of sensitive content

      Depiction or discussion of sexual content

      Supervision

      Adult supervision required

      Licence

      This content is © Oak National Academy Limited (2026), licensed on Open Government Licence version 3.0
      except where otherwise stated. See Oak's terms & conditions
      (Collection 2).

      Lesson video

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      Prior knowledge starter quiz

      6 Questions

      Q1.
      Which hormone is not involved in controlling the menstrual cycle?

      progesterone
      follicle stimulating hormone
      Correct answer: testosterone
      luteinising hormone
      oestrogen

      Q2.
      What does follicle stimulating hormone (FSH) cause?

      fertilisation
      ovulation
      Correct answer: follicles to mature
      menstruation
      Correct answer: secretion of oestrogen

      Q3.
      What does fertilisation produce?

      An image in a quiz
      Correct Answer: A zygote, zygote, fertilised egg

      Q4.
      Which hormone causes ovulation?

      Correct Answer: LH, Luteinising hormone, Luteinising

      Q5.
      Match the part to a description of its function.

      An image in a quiz
      Correct Answer:A,The egg travels down these oviducts.

      The egg travels down these oviducts.

      Correct Answer:B,Eggs are released by the ovaries.

      Eggs are released by the ovaries.

      Correct Answer:C,The cervix is the neck of the uterus.

      The cervix is the neck of the uterus.

      Correct Answer:D,Sperm is deposited in the vagina during sexual intercourse.

      Sperm is deposited in the vagina during sexual intercourse.

      Correct Answer:E,The uterus is where a fertilised egg will embed and grow until birth.

      The uterus is where a fertilised egg will embed and grow until birth.

      Q6.
      Put these steps in order to describe the menstrual cycle, starting with menstruation.

      An image in a quiz
      1 - uterus lining breaks down and leaves the body
      2 - follicle stimulating hormone (FSH) stimulates a follicle to mature
      3 - oestrogen stimulates the release of luteinising hormone (LH)
      4 - ovulation
      5 - progesterone is released to maintain the womb lining
      6 - progesterone levels drop
      Q6 Dee-sign/Shutterstock.com

      6 Questions

      Q1.
      True or false? Infertility only affects females.

      true
      Correct answer: false

      Q2.
      What can cause infertility?

      regular ovulation
      Correct answer: low sperm count
      Correct answer: low levels of specific reproductive hormones
      keeping fit by running
      Correct answer: low quality sperm

      Q3.
      Which hormones can be used to increase fertility in females?

      progesterone
      Correct answer: FSH
      oestrogen
      Correct answer: LH
      testosterone

      Q4.
      Put these stages of IVF in the right order.

      An image in a quiz
      1 - FSH given to female to develop eggs.
      2 - LH given to trigger egg release.
      3 - Eggs are extracted.
      4 - Eggs incubated with sperm.
      5 - Fertilised eggs stimulated to divide into an embryo.
      6 - Embryos implanted into mother’s uterus.

      Q5.
      What are the risks associated with in-vitro fertilisation (IVF) treatment?

      Correct answer: may lead to multiple births
      Correct answer: emotionally stressful for the couple
      not all embryos are implanted
      Correct answer: hormones can have side effects

      Q6.
      True or false? Each cycle of IVF has a 50% chance of success.

      true
      Correct answer: false

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